The Microbial fermentation technology involves the usage of microorganisms for producing valuable products that have immense medical and industrial applications in biotechnology.
The Microbial fermentation technology involves the usage of microorganisms for producing valuable products that have immense medical and industrial applications in biotechnology. The technology is growing rapidly worldwide due to economical and higher production of microbial products for various industries, including pharmaceuticals, chemicals, food & feed, among others. Furthermore, expansion of research and development activities, technological advancements, growing product awareness, coupled with new product launches are the major factors fueling the market growth. For instance, in June 2022, Microbiosci launched fermentation quality control system to aid culturing and propagation of microbial strains. Moreover, exhausting fossil fuel reserves and rising gasoline prices have increased the demand in chemical sectors for diverse products such as alcohols, alkaloids, enzymes, and amino acids among others. These products can be efficiently produced by using microbial fermentation technologies which can significantly boost the market growth.
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On the basis of products market is segmented into:
- Medical
- Antibiotics
- Probiotics
- Monoclonal Antibodies
- Recombinant Proteins
- Biosimilars
- Industrial
- Enzymes
- Amino acids
- Others
Antibiotics are one of the major products in the medicinal segment, as they are used in treating and preventing various bacterial infections. Antibiotics development in microbial systems is usually rapid and can be optimized for greater yield. There has been an increase in the demand for manufacturing solutions for antibody fragments, nanobodies, scaffolds and bioconjugates over few years, that is driving the key market players for expansion of their fermentation facilities. For instance, in August 2020, Lonza extended its manufacturing facility scale in Switzerland by 3,000 liters to address the growing demand for microbial manufacturing solutions.
Similarly, synthesis of enzymes through submerged and solid-state fermentation technique is more efficient when using microbes, as compared to the use of plants or animal-based entities. It is also facile to produce enzymes on large scales through fermentation techniques and they can be modified through various biochemical and molecular methods. Furthermore, proteases are one of the most important enzymes for various industrial applications, and accounts for nearly 60% of total enzyme sale. Availability of a variety of microbes for production of this enzyme, such as Bacillus licheniformis, Bacillus amyloliquifaciens, and Aspergillus niger thatare commonly used is expected to boost the adoption of fermentation techniques.
Driver
Fermentation technology has been a popular biological process in a variety of industrial applications for many decades due to its low cost, high specificity, ease of response, and versatility. While microbial fermentation has historically been employed mainly for food preservation, it has experienced a significant increase in application in recent years due to promising results and the prospect of developing new bioprocesses and products with its assistance. Modern industry has extended applications to generate a wide range of biotechnology products, including biofuels, biochemicals, biopharmaceuticals, biosimilar, and biomolecules, by combining the basic idea of fermentation technology with developments in genetic engineering.
Furthermore, rising gasoline prices and dwindling fossil fuel reserves have broadened the applicability of the microbial fermentation process in the chemical sector, producing products such as alcohols, enzymes, organic acids, amino acids, vitamins, alkaloids, and Xanthan. Rising global demand for these goods is expected to play a significant effect in assisting the global microbial fermentation market to expand at a promising rate in the coming years.
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Restraint
Microbial fermentation is a slow inefficient process that is anticipated to produce a significant barrier in terms of fulfilling the demand cycle. In addition, the cost associated with the storage of the product and the process of fertilization is quite high. Moreover, some of the end products of Microbial fermentation are toxic to nature such as ethanol which is very toxic to plants.
Key Players
- Biocon
- Novozymes
- Lonza
- F. Hoffmann-La Roche AG
- Amyris
- BioVectra
- DSM
- TerraVia Holdings, Inc.
- Danone Ltd.
- United Breweries Ltd.
Market Segmentation
- By Product
- Medical
- Antibiotics
- Probiotics
- Monoclonal Antibodies
- Recombinant Proteins
- Biosimilars
- Industrial
- Enzymes
- Amino acids
- Others
- Medical
- By End-user
- Bio-Pharmaceutical Companies
- Contract Research Organizations (CROs) and Contract Manufacturing Organizations (CMOs)
- Academic Research Institutes
- Others
- By Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
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