CHICAGO & SACRAMENTO, Calif.--(BUSINESS WIRE)--Merge Healthcare (NASDAQ: MRGE), a leading provider of healthcare enterprise imaging and interoperability solutions, and Ophthalmic Imaging Systems (OIS) (OTCBB: OISI), a leading provider of digital imaging and informatics solutions for ophthalmology and other medical specialties, today announced the signing of a definitive merger agreement pursuant to which Merge Healthcare will acquire OIS.