Mako Surgical Corp. (MAKO) plunged as much as 41 percent after cutting its sales forecast for the RIO robotic arm orthopedic system for the second time in two months. Mako fell 39 percent to $15.01 at 10:06 a.m., after dropping to as low as $14.62 in the biggest intraday decline since the shares began trading in February 2008. The shares had fallen 2.4 percent this year through yesterday. Based on results from the first six months, 42 to 48 of the systems may be sold this year, the Fort Lauderdale, Florida- based company said in a statement yesterday. On May 7, Mako trimmed the forecast to 52 to 58 systems from as much as 62.