HCA Healthcare Uses Its COVID-19 Registry by Forming Consortium With AHRQ and Research Institutions to Accelerate COVID-19 Research

As a learning health system, HCA Healthcare collects and analyzes data from its approximately 35 million annual patient encounters to develop technologies and best practices to improve patient care. With support from HCA Healthcare’s Sarah Cannon Research Institute and its precision medicine platform, Genospace, HCA Healthcare created a COVID-19 patient registry at the outset of the pandemic that has since captured data from treating more suspected and positive COVID-19 cases than any other health system in the United States, including more than 110,000 patients who were admitted for inpatient care in 2020.

“Scale accelerates learning. As HCA Healthcare’s learning network has treated more COVID-19 inpatients than any other health system in the U.S., this innovative public, private and academic sector partnership accelerates the understanding of COVID-19 and its treatment in a manner that would be difficult to replicate elsewhere and serves as a model for addressing the nation’s most pressing healthcare questions,” said Dr. Jonathan Perlin, president, clinical operations group, and chief medical officer of HCA Healthcare.

The COVID-19 Consortium of HCA Healthcare and Academia for Research GEneration (CHARGE) provides a framework for cooperation and coordination among all members to pose and test research questions, scrutinize and validate methods, and, most importantly, share and act on ambitious and innovative ideas that will help lead to impactful results. The group will use a technology platform, provided by DataFleets, that allows multiple collaborators to explore trends in a protected environment that obscures individually-identifying information.

“AHRQ is pleased to have been part of establishing this innovative partnership,” said David Meyers, MD, Acting Director, AHRQ. “We believe it has both the potential to rapidly produce new evidence to improve the safety and quality of care for people with COVID-19 and serve as a model for the development of a national learning health system. Using data to produce new evidence that enhances the quality, safety and value of healthcare delivery is at the core of AHRQ’s mission.”

Members of COVID-19 CHARGE Include:

• HCA Healthcare / HCA Healthcare Research Institute / Sarah Cannon Research Institute
• Agency for Healthcare Research and Quality (AHRQ)
• Columbia University
• Duke University
• Harvard Pilgrim Health Care Institute
• HOspital MEdicine Reengineering Network (HOMERuN), which includes University of California San Francisco, Baystate Medical Center, Beth Israel Deaconess Medical Center, and Brigham and Women’s Hospital
• Johns Hopkins University
• Meharry Medical College

The consortium will start with retrospective studies in the short term, such as evaluating the efficacy and safety of treatments used for COVID-19, improving overall understanding of the root cause for clinical outcomes, and developing novel predictive models. The insights gained from this research may lead to future clinical trials.

“Access to HCA Healthcare’s vast data repository will greatly accelerate the pace of discovery of new knowledge related to systems and approaches to care for patients with COVID-19. To put it succinctly, this initiative will help save lives,” said Shoshana J. Herzig, MD, MPH, Director of Hospital Medicine Research, Beth Israel Deaconess Medical Center.

The HCA Healthcare Research Institute leverages the capabilities and expertise of HCA Healthcare’s Sarah Cannon Research Institute to expand research support beyond its core expertise in oncology. Sarah Cannon Research Institute is one of the world’s leading clinical research organizations, conducting community-based clinical trials throughout the United States and United Kingdom. HCA Healthcare and HRI believe that collaboration with institutions focused on research related to the SARS-CoV-2 virus and COVID-19 global pandemic leverages the collective expertise of the members involved, advancing institutional and national research, scientific, and clinical missions for the benefit of humanity.

About HCA Healthcare

Nashville-based HCA Healthcare is one of the nation’s leading providers of healthcare services comprising more than 2,000 sites of care, including 187 hospitals, surgery centers, freestanding ERs, urgent care centers, and physician clinics, in 21 states and the United Kingdom. With its founding in 1968, HCA Healthcare created a new model for hospital care in the United States, using combined resources to strengthen hospitals, deliver patient-focused care and improve the practice of medicine. HCA Healthcare has conducted a number of clinical studies, including one that demonstrated that full-term delivery is healthier than early elective delivery of babies and another that identified a clinical protocol that can reduce bloodstream infections in ICU patients by 44 percent. HCA Healthcare is a learning health system that uses its more than 35 million annual patient encounters to advance science, improve patient care and save lives. Please click here to connect with HCA Healthcare on social media.

About Sarah Cannon

Sarah Cannon Research Institute is one of the world’s leading clinical research organizations conducting community-based clinical trials. A leader in drug development, Sarah Cannon has led more than 450 first-in-human oncology clinical trials since its inception in 1993 and has been a clinical trial leader in the majority of approved cancer therapies over the last 10 years. Beyond cancer, Sarah Cannon has a dedicated team of experts leading HCA Healthcare’s clinical research platform in many other critical therapeutic areas. To learn more about Sarah Cannon, visit sarahcannon.com.

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