GENEART AG Extends Strategic Partnership with QIAGEN Inc. to Commercialize Synthetic Human Genes

Regensburg, September 04, 2008 - GENEART (Frankfurt, Entry Standard, G6A) today announced the extension of its strategic collaboration with QIAGEN (Nasdaq: QGEN; Frankfurt, Prime Standard: QIA). So far, the complete set of optimized synthetic human genes sold via QIAGEN’s web portal GeneGlobe (“QIAgenes”) was designed for the production in E.coli bacteria only. The new set of genes will now be optimized for the use in insect or mammalian cells. With this offer, customers from academia as well as from pharmaceutical and biotech companies now can order optimized synthetic genes for use in mammalian and insect cells online via GeneGlobe. All QIAgenes are optimized and synthesized by GENEART.

“With the expansion of QIAgenes Expression Kits to include expression constructs that can be transfected into insect or mammalian cells, we are addressing a significant unmet customer need,” says Dr. Ute Boronowsky, Global Product Manager at QIAGEN. “Since the launch of our expression kits for use in E. coli cells in May, we have received a high number of requests for these two additional options. Customer service is a core commitment of QIAGEN and GENEART, and we are proud we have been able to respond to this need so quickly.”

“Low success rates together with limited yields in protein expression have always been a major challenge for scientists”, says Prof. Dr. Ralf Wagner, CEO/CSO of GENEART. “With our GeneOptimizer® and GeneAssembler® technology we are able to overcome this bottleneck for research. Validation studies have shown that genes optimized and synthesized by GENEART yield up to 50 fold more protein than conventional methods using “natural genes”, and achieve high success rates of expression of more than 90%.

With QIAgenes the collaboration partners succeeded in making human genes available in a standardized format for scientists all over the world. Customers choose the gene or protein sequence of their choice via the GeneGlobe web portal and receive the corresponding QIAgene by mail. With this service the marketing of QIAgenes as standardized catalogue product perfectly complements GENEART’s existing business to tailor gene sequences for individual customer requests.

For further inquiries, please contact:

Bernd Merkl GENEART AG Josef-Engert-Str. 11 93053 Regensburg Germany Phone: +49-(0)941-942 76-638 Fax: +49-(0)941-942 76-711 ir@geneart.com http://www.geneart.com

Frank Ostermair Better Orange IR & HV AG Haidelweg 48 81241 Munich Germany Phone: +49-(0)89-8896906-10 Fax: +49-(0)89-8896906-66 info@better-orange.de http://www.better-orange.de

Legal Information

This document may contain estimates, prognoses and opinions about company plans and objectives, products or services, future results, opinions about these results or opinions leading up to these results. All these projections into the future are subject to risk, uncertainty and unforeseeable change outside the control of the GENEART Group. Many factors may lead to actual results, which considerably deviate from the given projections for these results.

About Geneart: In 2000, GENEART entered the gene synthesis market and has since become the global market leader. Today, the company is one of the leading specialists in the synthetic biology field. Experts at GENEART provide key technologies for the development and production of new therapeutics and vaccines. Customers also take advantage of GENEART services to customize enzyme attributes, such as the attributes of enzymes used as detergent additives, and to construct bacteria, which produce complex biopolymers or break down polymers, such as synthetics, petroleum components, etc. Our production and service spectrum spans a wide range, from the production of synthetic genes according to DIN EN ISO 9001-2000, to the creation of gene libraries in the combinatorial biology, to the development and production of DNA-based biologically active substances. The GENEART AG in Regensburg (Germany) and the subsidiary GENEART Inc. in Toronto (Canada) employ more than 190 people. Since May 2006, GENEART is listed on the German Stock Exchange.

About QIAGEN:

QIAGEN N.V., a Netherlands holding company, is the leading global provider of sample and assay technologies. Sample technologies are used to isolate and process DNA, RNA and proteins from biological samples such as blood or tissue. Assay technologies are used to make such isolated biomolecules visible. QIAGEN has developed and markets more than 500 consumable products as well as automated solutions for such consumables. The company provides its products to molecular diagnostics laboratories, academic researchers, pharmaceutical and biotechnology companies, and applied testing customers for purposes such as forensics, animal or food testing and pharmaceutical process control. QIAGEN’s assay technologies include one of the broadest panels of molecular diagnostic tests available worldwide. This panel includes the only FDA-approved test for human papillomavirus (HPV), the primary cause of cervical cancer. QIAGEN employs more than 2,800 people in over 30 locations worldwide. Further information about QIAGEN can be found at www.qiagen.com.

GENEART Extends Strategic Partnership with QIAGEN to Commercialize Synthetic Human Genes: http://hugin.info/136633/R/1248436/270677.pdf

Copyright © Hugin AS 2008. All rights reserved. Contact: Source: Geneart AG

MORE ON THIS TOPIC