Genaera Corporation To Present At CIBC World Markets Annual Biotechnology & Specialty Pharma Conference

PLYMOUTH MEETING, Pa., April 3 /PRNewswire-FirstCall/ -- Genaera Corporation will present at the CIBC World Markets Annual Biotechnology & Specialty Pharma Conference being held April 4-5, 2006 at the Millennium Broadway Hotel in New York City. John L. Armstrong, Jr., President and Chief Executive Officer, will provide a corporate overview on Tuesday, April 4, 2006 at 11:00 a.m. in room 3.02/3.03.

The presentation will highlight clinical progress with Genaera’s lead product candidate, EVIZON(TM) (squalamine lactate), a first-in-class intravenous anti-angiogenic being studied for the treatment of wet age-related macular degeneration (AMD). The Company’s other development programs, including squalamine in cancer, the mucoregulator LOMUCIN(TM) for cystic fibrosis, the IL-9 antibody in asthma, and trodusquemine for obesity, will also be reviewed.

To access the live or archived audio and slide deck via the Internet, please log on to the home page of the Company’s website, http://www.genaera.com. Please connect to the site prior to the presentation to ensure adequate time for any software download that may be needed to hear the webcast.

About Genaera Corporation

Genaera Corporation is a biopharmaceutical company committed to developing medicines to address substantial unmet medical needs in major pharmaceutical markets. The Company has four products in development for the treatment of eye, cancer and respiratory disorders. EVIZON(TM) (squalamine lactate) is Genaera’s lead product in development for ophthalmic indications, specifically wet age-related macular degeneration (AMD). Genaera’s other programs include: squalamine for the treatment of cancer; interleukin-9 antibody, a respiratory treatment based on the discovery of a genetic cause of asthma; and LOMUCIN(TM), a mucoregulator to treat the overproduction of mucus and secretions involved in many forms of chronic respiratory disease.

This announcement contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that are subject to risks and uncertainties, known and unknown. Forward-looking statements reflect management’s current views and are based on certain expectations and assumptions. Such statements include, among others, statements regarding preliminary results, future clinical development plans and prospects for Genaera’s programs. You may identify some of these forward-looking statements by the use of words in the statements such as “anticipate,” “develop,” “expect,” and “continue,” or other words of similar meaning. Genaera’s actual results and performance could differ materially from those currently anticipated and expressed in these and other forward-looking statements as a result of a number of risk factors, including, but not limited to; Genaera’s history of operating losses since inception and its need for additional funds to operate its business; the costs, delays and uncertainties inherent in scientific research, drug development, clinical trials and the regulatory approval process; the risk that clinical trials for Genaera’s product candidates, including EVIZON(TM) (squalamine lactate) and squalamine, may be delayed or not be successful; the risk that Genaera may not obtain regulatory approval for its products, whether due to adequacy of the development program, the conduct of the clinical trials, changing regulatory requirements, different methods of evaluating and interpreting data, regulatory interpretations of clinical risk and benefit, or otherwise; Genaera’s reliance on its collaborators, in connection with the development and commercialization of Genaera’s product candidates; market acceptance of Genaera’s products, if regulatory approval is achieved; competition; general financial, economic, regulatory and political conditions affecting the biotechnology and pharmaceutical industry; and the other risks and uncertainties discussed in this announcement and in Genaera’s filings with the U.S. Securities and Exchange Commission, all of which are available from the Commission in its EDGAR database at http://www.sec.gov as well as other sources. You are encouraged to read these reports. Given the uncertainties affecting development stage pharmaceutical companies, you are cautioned not to place undue reliance on any such forward-looking statements, any of which may turn out to be wrong due to inaccurate assumptions, unknown risks, uncertainties or other factors. Genaera does not intend (and it is not obligated) to publicly update, revise or correct these forward-looking statements or the risk factors that may relate thereto.

Genaera Corporation

CONTACT: Genaera Corporation Investor Relations, +1-610-941-5675; orCeleste Duncan, The Trout Group (Investor Inquiries), +1-212-477-9007 ext.45, or Mike Beyer, Sam Brown Inc. (Media Inquiries), +1-773-463-4211,beyer@sambrown.com, both for Genaera Corporation

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