Expression Analysis and Althea Technologies in Strategic Alliance to Expedite Genomic Biomarker Identification and Application

SAN DIEGO, Oct. 11 /PRNewswire/ -- Through a collaborative agreement, Althea Technologies, Inc., a leading provider of innovative technologies, quantitative gene expression testing and cGMP pharmaceutical manufacturing services and Expression Analysis, Inc., (EA) a full service GLP microarray genetics testing, analysis and data management organization, have developed a streamlined approach for the identification and application of genomic biomarkers. EA and Althea will be offering a comprehensive "Signature Discovery(TM) Service" that will allow researchers and drug developers to progress from global to focused gene expression analysis, enabling the discovery and subsequent application of validated gene expression biomarkers for a targeted disease or drug activity. Both firms will contribute to the design, data mining and analysis, and data management of specialized studies that will take advantage of EA's expertise in the application of the Affymetrix GeneChip(R) microarray technology and Althea's proprietary eXpress Profiling(TM) technology which allows for high throughput gene expression analysis.

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Dr. Francois Ferre, co-President and co-CEO of Althea Technologies said the agreement is a significant strategic advance. "Through our alliance with Expression Analysis, we are able to provide a direct path from global gene expression profiling to identifying those focused sets of genes that are the key to a research goal. Whether it is discovering disease classifiers, characterizing targets and pathways, evaluating lead compounds or creating toxicological profiles, the two companies are now able to provide a complete analytical solution. EA, as the premier provider of microarray testing with a clear service focus is a wonderful partner," Ferre said.

"Our agreement with Althea establishes an important resource for academic, biotechnology, pharmaceutical and other human health related organizations," said Steve Casey, EA's founder and chief operating officer. "Microarray technology use continues to expand rapidly and now, through this alliance we can collaboratively design studies which will efficiently employ gene expression technologies to identify solutions for these genomic inquiries."

About Althea Technologies

Althea Technologies, a leading San Diego-based pharmaceutical services firm, provides critical manufacturing and development services that support researchers worldwide in their advancement of novel therapies and efforts to apply new genomic information. Althea has introduced new services and technologies for the identification and understanding of gene signatures with innovative tools such as the company's proprietary eXpress Profiling(TM) technology. Additionally, Althea provides services including cGMP contract manufacturing of recombinant proteins and DNA-based therapeutics and vaccines, aseptic filling, and gene quantification using real-time PCR and gene expression analysis under GLP conditions. For more information, visit http://www.altheatech.com/.

About Expression Analysis

Expression Analysis, Inc., (EA) (http://www.expressionanalysis.com/) is a full- service microarray genetics testing and analysis organization dedicated to providing clients with the highest quality genomic processing and data analysis services using Affymetrix GeneChip(R) brand technology. This technology applies the principles of semiconductor technology to life sciences, making it possible to qualitatively and quantitatively measure gene expression levels in a number of biologically relevant organisms, quickly and with more reliable results. EA is one of the few U.S.-based authorized service providers for Affymetrix (http://www.affymetrix.com/), a California-based company that develops and commercializes systems to help researchers explore the relationship between genes and human health.

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CONTACT: Alan Moore of Althea Technologies, +1-858-882-0205,amoore@altheatech.com; or Katherine Smart of Expression Analysis,+1-919-313-7612, ksmart@constellagroup.com