Analyzing existing gene expression datasets, researchers at Stanford University have discovered an 11-gene set that allows them to identify patients with sepsis and distinguish them from patients with systemic inflammation from non-infectious causes. The team is currently conducting clinical studies to confirm their findings, with the goal of developing a rapid clinical sepsis assay.
Results from the study that identified the 11-gene set were published online todayin Science Translational Medicine. “We’ve certainly shown that there is information in the gene expression space that can aid in diagnostics that’s not being used now,” Tim Sweeney, the study’s first author and a surgery resident at Stanford, told GenomeWeb. “What we’re looking forward to is showing that, in combination with current diagnostics, this will improve our ability to diagnose sepsis,” he said.
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