Data Published in the Proceedings of the National Academy of Sciences Highlight the Potential of Cyclacel Pharmaceuticals, Inc.'s Targeted CDK Inhibitors in Breast Cancer

BERKELEY HEIGHTS, N.J., Feb. 17, 2011 (GLOBE NEWSWIRE) -- Cyclacel Pharmaceuticals, Inc. (Nasdaq:CYCC) (Nasdaq:CYCCP) (Cyclacel or the Company), today announced the publication of preclinical data in the Proceedings of the National Academy of Sciences (PNAS), demonstrating that cyclin E plays a major role in making Human Epidermal growth factor Receptor 2 positive (HER2+) breast cancer resistant to trastuzumab (Herceptin®), a widely used medicine for breast cancer patients who test positive for HER2. The publication provides a rationale for exploring Cyclacel’s orally available CDK inhibitors in this patient population.