SAN DIEGO, CA -- (MARKET WIRE) -- March 14, 2007 -- Cypress Bioscience, Inc. (NASDAQ: CYPB) today announced its financial results for the fourth quarter and year ended December 31, 2006. For the quarter ended December 31, 2006, the Company reported a net loss of approximately $1.1 million or $0.03 per share basic and diluted compared to a net loss of approximately $1.8 million or $0.06 per share basic and diluted for the corresponding period in 2005. For the year ended December 31, 2006, the Company reported a net loss of approximately $8.2 million or $0.26 per share basic and diluted compared to a net loss of approximately $8.6 million or $0.28 per share basic and diluted for the corresponding period in 2005. At December 31, 2006, the Company had cash, cash equivalents and investments totaling $102.8 million.