CuraGen Corporation To Discuss Third Quarter 2005 Results Via Conference Call On October 27, 2005

BRANFORD, Conn., Oct. 20 /PRNewswire-FirstCall/ -- CuraGen Corporation today announced that Company executives will hold a conference call and webcast to discuss CuraGen and 454 Life Sciences’ third quarter 2005 results at 10:00 a.m. Eastern time on Thursday, October 27, 2005. A press release outlining third quarter 2005 results will be issued prior to the call.

Date: Thursday, October 27, 2005 Time: 10:00 a.m. ET Dial-in: 877-272-5391 (domestic) 706-758-4315 (international) Passcode: 1380519 Webcast: Access to the live webcast is available on CCBN and at http://www.curagen.com.

A replay of the conference call will be available starting at 1:00 p.m. Eastern time on Thursday, October 27, 2005 through Sunday, November 27, 2005 by dialing 800-642-1687 (domestic) or 706-645-9291 (international). The passcode for the replay is 1380519. An archive of the webcast will be available for 30 days at http://www.curagen.com.

About CuraGen

CuraGen Corporation is a biopharmaceutical company dedicated to improving the lives of patients by developing a pipeline of novel protein, antibody, and small molecule therapeutics in the areas of oncology, inflammatory diseases, and diabetes. CuraGen has established broad development alliances with Abgenix, TopoTarget, and Bayer, and its experienced preclinical and clinical teams are advancing the Company’s pipeline of products for unmet medical needs. The Company is headquartered in Branford, CT. For additional information please visit http://www.curagen.com.

CuraGen Contact: Glenn Schulman, Pharm.D. Assistant Director of Investor Relations gschulman@curagen.com 1-888-GENOMICS

CuraGen Corporation

CONTACT: Glenn Schulman, Pharm.D., Assistant Director of InvestorRelations of CuraGen, +1-888-GENOMICS, gschulman@curagen.com

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