Earlier this October, Creative Peptides, one of the world’s leading peptide manufacturers, has announced a series of peptide modification services. Now this company makes a further step and releases post-translational modification service.
Earlier this October, Creative Peptides, one of the world’s leading peptide manufacturers, has announced a series of peptide modification services. Now this company makes a further step and releases post-translational modification service.
Peptide modifications are often made to obtain the desired stability and selectivity for the target of interest and to optimize the structures of lead peptide for better activity and potency, post-translational modification is a sub-branch of peptide modification and it plays an important role in virtually all biological processes.
“When proteins or peptides are catalyzed by enzymes and complete ribosomal translation, modifications such as altering the electrostatic charge, hydrophilicity, and conformation can be made to alter the physicochemical properties of peptides, thereby modulating their ability to specifically bind to the protein of interest,” noted Head of Creative Peptides’ synthesis businesses Dr. Robert Martinez.
“Some nascent peptide chains can be directly folded into the final three-dimensional structure after being released from the ribosome, but in most cases, the nascent peptide undergoes a series of modifications before they become mature protein product and begin to function. In general, post-translational modifications are made to meet certain functional needs, while in another case, the need to fold into a natural conformation,” further explains Dr. Robert.
Based on different needs of customers, the following post-translational modifications are now available:
- Phosphorylation
- Glycosylation
- Acetylation
- Sulfation
- Hydroxylation
- Prenylation
To know more detailed information about post-translational modification service, please visit https://www.creative-peptides.
About Creative Peptides
Staffed with experts of multiple fields in peptide technology and synthetic chemistry, Creative Peptides not only provides a comprehensive collection of peptides like checkpoint inhibitors, therapeutic peptides, cosmetic peptides and catalog peptides, but also dedicates to solving the problems that trouble its clients by offering various custom peptide synthesis services, including custom conjugation, peptide nucleic acid synthesis, De novo peptide design,oligopeptide synthesis, peptide lead optimization, neoantigen peptides vaccine synthesis, etc.
