Shirley, NY--According to a senior scientist at Creative Biogene, which is a US-based biotech company, Gene Expression Cell Lines have been successfully updated recently. The senior scientist told us what is Gene Expression and why they want to do more on it. Based on experience in the field, Creative Biogene with its professional team finally updated Gene Expression Cell Lines, which can be customized to various research needs.
What Is Gene Expression? Gene expression refers to the process when cells transfect or transduct the genetic information in DNA sequences to certain bio-active proteins. This process is commonly used by all known life. For instance, eukaryotes, prokaryotes, etc. However, the over-expression of proteins is very censorious for a great number of applications, such as studying the function of the gene, and in functional assays and screens. In terms of mammalian cells, they can provide advantages in post-translational modification and protein folding. Both of them are extremely important in the producing of eukaryotic proteins.
Here are several examples, like antibodies, recombinant proteins and so on. On the other hand, stable cell lines overexpressing specific proteins have not only integrated GOI in the genome, but also are expensive and crucial parts for life science study.
Why Scientists Should Work on Gene Expression Cell Lines? As the director said, “Gene Expression Cell Lines include construct generation, stable cell clones selection, as well as gene expression evaluation...Creative Biogene has overcome the challenges such as high cost, necessary experience, and expertise. More studies on gene expression can result in more findings of genes, cells, and even clones. Therefore, more attention will be paid to gene expression cell lines”.
What’s more, transfection or transduction is performed on target cells and used to select stable cell clones. Besides, the gene expression in stable cell clones can be evaluated via one or several assays, for instance ELISA, real-time PCR, or reporter assays etc.
Additionally, a certain gene of interest can be constructed into an appropriate mammalian expression vector or a lentiviral vector, after which generating high titer lentivirus is needed. According to different requirements, different but suitable strategy and corresponding vector system will be chosen.
Creative Biogene’ manager also explained that services for generation of stable cell lines that can overexpress virtually any protein of interest in cell line of choice is also available.
For more related info about Custom Gene Expression Cell Lines, please call at 1-631-626-9181 or you can visit http://www.creative-biogene.com/Services/Stable-cell-line-generation/Custom-Gene-Expression-Cell-Lines.html for more details. This is written by Amy Collins of Creative Biogene, a US-based biotech company.
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What Is Gene Expression? Gene expression refers to the process when cells transfect or transduct the genetic information in DNA sequences to certain bio-active proteins. This process is commonly used by all known life. For instance, eukaryotes, prokaryotes, etc. However, the over-expression of proteins is very censorious for a great number of applications, such as studying the function of the gene, and in functional assays and screens. In terms of mammalian cells, they can provide advantages in post-translational modification and protein folding. Both of them are extremely important in the producing of eukaryotic proteins.
Here are several examples, like antibodies, recombinant proteins and so on. On the other hand, stable cell lines overexpressing specific proteins have not only integrated GOI in the genome, but also are expensive and crucial parts for life science study.
Why Scientists Should Work on Gene Expression Cell Lines? As the director said, “Gene Expression Cell Lines include construct generation, stable cell clones selection, as well as gene expression evaluation...Creative Biogene has overcome the challenges such as high cost, necessary experience, and expertise. More studies on gene expression can result in more findings of genes, cells, and even clones. Therefore, more attention will be paid to gene expression cell lines”.
What’s more, transfection or transduction is performed on target cells and used to select stable cell clones. Besides, the gene expression in stable cell clones can be evaluated via one or several assays, for instance ELISA, real-time PCR, or reporter assays etc.
Additionally, a certain gene of interest can be constructed into an appropriate mammalian expression vector or a lentiviral vector, after which generating high titer lentivirus is needed. According to different requirements, different but suitable strategy and corresponding vector system will be chosen.
Creative Biogene’ manager also explained that services for generation of stable cell lines that can overexpress virtually any protein of interest in cell line of choice is also available.
For more related info about Custom Gene Expression Cell Lines, please call at 1-631-626-9181 or you can visit http://www.creative-biogene.com/Services/Stable-cell-line-generation/Custom-Gene-Expression-Cell-Lines.html for more details. This is written by Amy Collins of Creative Biogene, a US-based biotech company.
Help employers find you! Check out all the jobs and post your resume.
