Romainville, France - January the 08th, 2007 - Cellectis S.A., a biotechnology company specialized in genome engineering and developing a new range of products for the custom rewriting of DNA sequences for the research, healthcare and industrial fields, announced today the publication of a paper entitled “A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences” in the prestigious journal Nucleic Acids Research (http://nar.oxfordjournals.org/cgi/content/full/34/22/e149- Nucleic Acids Research, 2006, Vol. 34, No. 22 e149 - that publishes the results of leading edge research into physical, chemical, biochemical and biological aspects of nucleic acids and proteins involved in nucleic acid metabolism and/or interactions. This article describes the first artificial homing endonucleases whose specificity has been entirely redesigned to cleave a naturally occurring sequence.
