Cannabis can reduce allergic skin reactions, a new study suggests. The findings may lead to new drugs based on tetrahydrocannabinol (THC), the active ingredient in the plant, to treat allergy and autoimmune disorders.Andreas Zimmer at the University of Bonn in Germany, and colleagues created a group of mice that lack the receptor for endocannabinoids – forms of THC produced naturally in the body. The team noticed that the mice soon developed a severe skin allergy to the nickel in the metal tags the researchers had fastened to their ears.