NEW YORK--(BUSINESS WIRE)--April 11, 2006--Callisto Pharmaceuticals, Inc. (AMEX:KAL - News; FWB:CA4), a developer of new drug treatments in the fight against cancer and other major health threats, today released a letter to shareholders from CEO Dr. Gary S. Jacob. In the letter, Dr. Jacob outlines the Company’s significant business accomplishments during the first quarter of 2006 and cites key goals for Callisto’s drug development programs.