Boehringer Ingelheim today announces the next step in the clinical development of idarucizumab*, the investigational antidote for rapid reversal of dabigatran-induced anticoagulation. The specific antidote has already demonstrated immediate, complete and sustained reversal of the anticoagulant effect of dabigatran in healthy volunteers.2 Now the potential antidote will be investigated in the clinical setting in patients taking Pradaxa® (dabigatran etexilate).1 This is the first time that an antidote under development for a novel oral anticoagulant is investigated in a study in patients.1
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