PITTSBORO, NC--(Marketwire - December 10, 2007) - Biolex Therapeutics today announced that preclinical results of an anti-CD20 antibody optimized in its proprietary LEX System(SM) were presented yesterday at the 49th Annual Meeting of the American Society of Hematology (ASH) in Atlanta, Georgia. The results highlight the ability of the LEX System to produce an anti-CD20 antibody with an optimized glycosylation structure with enhanced antibody dependent cellular cytotoxicity (ADCC), more potent B-cell depletion, and potentially lower side effects compared to Rituxan® (rituximab), the current standard of care for the treatment of non-Hodgkin’s B-cell lymphoma. Biolex is developing BLX-301, a humanized anti-CD20 candidate incorporating the optimized glycosylation benefits of the LEX System.
