CAMBRIDGE, Mass.--(BUSINESS WIRE)-- KSQ® Therapeutics, a biotechnology company using its proprietary CRISPRomics® discovery platform to systematically screen the whole genome to identify optimal gene targets for oncology and autoimmune disease, announced it will present new data from its USP1 inhibitor program at the 32^nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (ENA 2020) taking place virtually October 24-25, 2020. Preclinical data on the company’s USP1 inhibitor program will be featured as part of a plenary session highlighting late breaking and best proffered papers, and the company will also present a poster featuring data on its lead USP1 candidate, KSQ-4279.

Presentation details:

Plenary Title: “USP1 inhibitors show robust combination activity and a distinct resistance profile from PARP inhibitors.”
Session Title: Plenary Session 1: Late Breaking and Best Proffered Papers
Session Date and Time: Saturday, Oct. 24, 2020, 3:05-4:35 PM CEST (9:05-10:35 AM ET)

Poster Title: “Development of KSQ-4279 as a first-in-class USP1 inhibitor for the treatment of BRCA-deficient cancers.”
Poster Number: 184
Session Code: 380
Poster Session Title: New Drugs
Session Date and Time: Saturday, Oct. 24, 2020

“We are pleased to present this exciting data on our industry-leading USP1 inhibitor program and our clinical candidate KSQ-4279 at this year’s ENA meeting,” stated Frank Stegmeier, Ph.D., Chief Scientific Officer at KSQ. “We believe USP1 inhibitors may have significant therapeutic benefit across a wide range of cancer types, in particular in combination with well-known standard-of-care therapies such as PARP inhibitors, and we’re excited to present data demonstrating that potential.”

The EORTC-NCI-AACR Symposium is hosted by the European Organization for Research and Treatment of Cancer (EORTC), the National Cancer Institute (NCI) and the American Association for Cancer Research (AACR). The Symposium brings together academics, scientists and pharmaceutical industry representatives from across the globe to learn the latest innovations in drug development, target selection, and the impact of new discoveries in molecular biology. To register for free visit www.eortc.org/ena.

About KSQ Therapeutics

KSQ® Therapeutics is advancing a pipeline of tumor- and immune-focused drug candidates for the treatment of cancer, across multiple drug modalities including targeted therapies, adoptive cell therapies and immuno-therapies. KSQ’s proprietary CRISPRomics® discovery engine enables genome-scale, in vivo validated, unbiased drug discovery across broad therapeutic areas. KSQ® was founded by thought leaders in the field of functional genomics and pioneers of CRISPR screening technologies, and the company is located in Cambridge, Massachusetts. For more information, please visit the company’s website at www.KSQtx.com.

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