BioSpace News Archive

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Manufacturing

As Amgen and Lilly Recommit, Puerto Rico Seeks To Regain Manufacturing Momentum

After suffering in the wake of expired tax incentives for pharmas, the island is trying to take advantage of geopolitics to grow its drug manufacturing sector.

February 3, 2026

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4 min read

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Nick Paul Taylor

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Drug Development

BioNTech’s Multi-Modality Play Outpaces Moderna’s mRNA-Focused Pipeline

After advancing in lockstep through the pandemic, the fortunes of the biotechs have diverged as their use of COVID-19 windfalls has taken shape.

February 3, 2026

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5 min read

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Nick Paul Taylor

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Obesity

Pfizer’s First Weight-Loss Data After Metsera Buy ‘Look Competitive’

With data from a mid-stage trial showing weight loss of up to 12.3% at 28 weeks in patients treated with PF’3944, “Pfizer is moving full speed into obesity clinical development,” BMO Capital Markets said Tuesday.

February 3, 2026

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2 min read

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Tristan Manalac

Weight loss

Novo’s Next-Gen Obesity Drug Beats Wegovy on Blood Sugar Control in Phase III

While CagriSema bested Novo Nordisk’s Wegovy on blood sugar control in a late-stage trial, the next-gen weight loss drug still has not met the pharma’s 25% weight loss goal.

February 3, 2026

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2 min read

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Tristan Manalac

Life is full of challenges and unexpected obstacles. Use these experiences as motivation to keep pushing forward and striving for your goals

Antibody-drug conjugate (ADC)

Daiichi Sankyo Dumps Next-Gen ADC From Development Pipeline

DS-9606 was supposed to be the first antibody-drug conjugate in Daiichi Sankyo’s line of anti-cancer assets to use a modified pyrrolobenzodiazepine payload.

February 3, 2026

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2 min read

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Tristan Manalac

Deals

Roche Keeps the Deals Coming With up to $1.7B SangeneBio RNAi Pact

The alliance will add to Roche’s RNAi efforts, which include the hypertension candidate zilbesiran, partnered with Alnylam under a July 2023 agreement.

February 3, 2026

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1 min read

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Tristan Manalac

Merck & Co. headquarters in Silicon Valley; Merck & Co. Inc. is an American multinational pharmaceutical company

Earnings

Merck Bats Away ‘Modest Growth’ Accusations, Touts Broad Pipeline

In its 2025 full year and fourth-quarter earnings call, Merck executives touted the merits of recent deals and what CEO Robert Davis called “probably the broadest and widest pipeline we’ve had in years.”

February 3, 2026

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2 min read

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Dan Samorodnitsky

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Earnings

Pfizer’s Early Metsera Data Leaves Analysts Wanting More

Analysts parsed the limited data available for Pfizer’s obesity candidate on the pharma’s fourth-quarter earnings call Tuesday, looking for any nugget of additional context.

February 3, 2026

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4 min read

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Annalee Armstrong

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Earnings

Novo Slides 14% as Early Q4 Results Predict Sales Decline for 2026

Novo Nordisk beat analyst expectations for the fourth quarter, but the result was overshadowed by softened expectations for this year.

February 3, 2026

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2 min read

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Annalee Armstrong

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Rare diseases

Rare Pediatric Disease Vouchers Reauthorized, PBM Reform Funded in Narrowly Passed Spending Bill

U.S. President Donald Trump signed a spending package into law Tuesday that reauthorizes the FDA’s previously stalled rare pediatric disease priority review voucher program, among other initiatives, while ending a three-day partial government shutdown.

February 3, 2026

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3 min read

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Heather McKenzie