SANTA CLARA, Calif.--(BUSINESS WIRE)--Jan. 26, 2006--Affymetrix, Inc., (Nasdaq:AFFX) today reported its results for the fourth quarter and fiscal year ended December 31, 2005. The Company reported net income of $24.8 million or $0.35 per diluted share in the fourth quarter of 2005, as compared to net income of $27.1 million or $0.41 per diluted share in the fourth quarter of 2004.