Acambis PLC Announces Appointment of New Chief Executive Officer

Cambridge, UK and Cambridge, Massachusetts – 7 March 2007 – Acambis plc (“Acambis”) (LSE: ACM) announces changes to its senior executive management team. Ian Garland, 41, is appointed as Chief Executive Officer with effect from 1 June 2007. He replaces Gordon Cameron who has served as CEO since 2004. Mr Cameron will remain in his current position to ensure a smooth transition until Ian Garland’s arrival. In addition, David Lawrence, Chief Financial Officer will leave the employment of the Company with immediate effect. He will be replaced by Elizabeth Brown as acting CFO.

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