Austin, Texas, April 24, 2014 (GLOBE NEWSWIRE) -- Xeris Pharmaceuticals, Inc. ("Xeris"), a clinical stage, specialty biopharmaceutical company developing novel, non-aqueous formulations of injectable drugs, announced today the dosing of the first subject in a Phase 2 clinical study of the company's stable liquid glucagon in an Insulet Corporation OmniPod® infusion pump in patients with type 1 diabetes under a new US Investigational New Drug (IND) application. Xeris' G-Pump™ (glucagon infusion), a room-temperature stable glucagon solution, is a potentially effective and convenient treatment for hypoglycemia or low blood sugar. Currently, no commercial glucagon product is approved for use in any infusion pump. Glucagon is only approved and available in emergency kits (GEKs) marketed by Eli Lilly and Company and Novo Nordisk for the treatment of severe hypoglycemia. However, with these products, glucagon is available only as a dry powder in a sealed vial that must be reconstituted using a water-filled syringe in a multi-step process prior to injection. Xeris' glucagon formulation is a stable, ready-to-inject liquid which can be packaged and delivered with a variety of devices including auto-injectors, multi-dose pens and pumps.
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