Continued Advancement of a New Full-Human CTLA-4 Antibody
NESS-ZIONA, Israel, June 6, 2018 /PRNewswire/ -- Tikcro Technologies Ltd. (OTCQB: TIKRF), a pre-clinical stage developer of antibodies for cancer immune-therapy, today reported its financial results for the first quarter ended March 31, 2018. Aviv Boim, CEO of Tikcro, commented, “We are pleased to report that our full human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blocking antibody continues to show strong comparative results in cancer inhibition animal models and in a wide set of in-vitro assays. We believe that this strong functionality is a result of the novel “pin-point” immunization approach we promote, which triggers an immune response to a selected 3-dimensional structure of a desired epitope. Treatment with a CTLA-4 blocking antibody has recently gained traction with efficacy data for additional clinical cancerous indications. In turn, we see an increased interest in our antibody from pharma companies who wish to enter this area. We intend to invest efforts to pursue market collaborations to further advance our new CTLA-4 antibody.” Recently, the U.S. Food and Drug Administration (FDA) approved a combination treatment of a CTLA-4 antibody with a PD-1 antibody for late stage renal cancer. This approval comes on top of previous approvals for sub-types of melanoma. Additional clinical indications are pending approval. The market size for CTLA-4 blocking antibodies exceeded $1 billion in 2017 and is expected to reach about $3 billion per annum by 2022. Several pharma companies, including Tikcro, are pursuing new CTLA-4 antibodies to further broaden its clinical scope and to reduce immune related adverse effects. Financial Results for the First Quarter Ended March 31, 2018 As of March 31, 2018, the company reported $6.2 million in cash and cash equivalents. About Tikcro Technologies Safe Harbor Statement
Tikcro Technologies Ltd. Condensed Balance Sheets (US dollars in thousands) ------------------------ March 31, December 31, 2018 2017 ---- ---- Unaudited Audited --------- ------- Assets Current assets Cash and cash equivalents $6,175 $6,562 Receivables and other financial asset 36 21 --- Total current assets 6,211 6,583 Property and equipment, net 126 125 Total assets $6,337 $6,708 ------ ------ Liabilities and Shareholders’ Equity Current liabilities Other current liabilities $277 $309 ---- ---- Shareholders’ equity 6,060 6,399 ----- ----- Total liabilities and shareholders’ equity $6,337 $6,708 ------ ------
Tikcro Technologies Ltd. Statements of Operations (US dollars in thousands, except per share data) ----------------------------------------------- Three Months Ended March 31, 2018 2017 ---- ---- Research and development expenses $223 $172 General and administrative expenses, net 149 145 --- --- Total operating expenses 372 317 --- --- Operating loss (372) (317) Financial income (expenses), net (5) 38 --- --- Net loss $(377) $(279) Basic and diluted net loss per share $(0.04) $(0.03) Weighted average number of shares used 9,879 9,879 computing basic and diluted loss per share
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Company Codes: OTC-PINK:TIKRF, OTC-QB:TIKRF |