January 21, 2005 -- Following the dominant pattern so far this year, stocks started off the day higher on Friday and then it was about midway through the session this time gave up their gains as the day wore on. The Centient Biotech 200 was lower by 19.87 points at 3320.31, a loss of .59%. Nevertheless, it was a good day to raise money on Wall Street, with an IPO that did very well in open trading, no less than 3 secondary offerings, and the second big pharma buy-out of a biotech in as many days. Priority Healthcare did well after receiving an analyst upgrade, and Cell Therapeutics moved up, with results expected soon from its nanotech cancer drug. Johnson & Johnson, however, faces some safety problems with an Alzheimer’s drug.