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NEW YORK, Aug. 1, 2013 (GLOBE NEWSWIRE) -- SIGA Technologies, Inc. (Nasdaq:SIGA) today announced that it has selected a lead candidate for its dengue fever antiviral program.
“Identifying a lead candidate is an early but crucial step in a long journey to develop a dengue fever drug,” said Dr. Dennis E. Hruby, SIGA’s Chief Scientific Officer. “Our new, orally bioavailable lead candidate compound appears to have a novel mechanism of action against all four serotypes of dengue virus in vitro at the nanomolar level, and to demonstrate efficacy in mouse models. Having selected a lead preclinical candidate compound, we intend to start scale-up and formulation work as we pursue Investigational New Drug (IND)-enabling studies.”
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