Researchers say they’ve identified tiny structures that may prepare the groundwork for how new cells form and function.These cellular structures, called GW bodies, play an important role in gene regulation (RNA interference), according to a team from the University of Florida, Gainesville. The discovery marks a major shift in the understanding of cell biology, and could aid the development of treatments for cancer and autoimmune diseases. It might also improve gene therapy, the researchers say.GW bodies are located in the jelly-like cytoplasm that surrounds the nucleus, and appear to help regulate genetic material called microRNA. MicroRNA typically switch genes off to control cell reproduction and development, but the Florida team found this process functioned poorly when GW bodies were absent.The study appears in the online issue of Nature Cell Biology.
