May 20, 2005 Behind monoclonal antibodies lies a 30-year-old technology, but monoclonals are hotter today than ever before. In 1975, Cesar Milstein and Georges Koehler discovered how to isolate monoclonal antibodies using hybridoma cells. But it was not until 1997 that monoclonal antibodies came of age and delivered a better therapeutic (though the first monoclonal antibody was approved in 1986). Today, they are taking the clinic by storm. We look at the science and the results of this remarkable scientific breakthrough...
