June 12, 2025 — Shanghai Escugen Biotechnology Co., Ltd. (“Escugen”) and Sovran Bio, Inc. (“Sovran” or “Sovran Bio”) jointly announced today the signing of a strategic collaboration agreement.
This collaboration aims to leverage Sovran's novel approach to broad-spectrum disease targeting and unique biologic architectures together with Escugen's proprietary EZWi-Fit® platform technology and deep development expertise to rapidly advance multiple novel antibody and antibody-drug conjugate (ADC) therapeutic product candidates to the clinical. Under the agreement, the parties will jointly contribute to partnered program research and development with shared upside.
Dr. David Meininger, Founder & CEO of Sovran, remarked that “the deal plays to the strengths of each company to quickly and efficiently translate new thinking on well-known therapeutic problems into better solutions for patients.”
Dr. Qing Zhou, Co-Founder and CEO of Escugen, stated that “this partnership marks a significant milestone for both companies to accelerate their R&D processes in bringing next-generation therapeutics to the global pharmaceutical market. A joint research effort also harvests tremendous global opportunities for both parties.”
About Sovran Sovran
Bio is a biopharmaceutical research and development company dedicated to
addressing unmet medical needs. The company is exploring novel approaches to
tumor-antigen specificity potentially applicable to any cancer. Pipeline
efforts include pursuit of additional solutions to challenges inherent to
broad-spectrum targeting in oncology, autoimmunity and other disease areas. For
more information, visit https://sovranbio.com/ and connect with us on LinkedIn. About
Escugen Escugen is
a clinical-stage biotechnology company located in Shanghai, China, focusing on
the development of innovative ADC drugs. Currently, Escugen's lead Trop-2 ADC
pipeline, ESG401, has entered Phase III clinical trials. Escugen's
next-generation linker-payload technology platform, EZWi-Fit®,
offers significant competitive advantages in terms of safety, efficacy,
anti-multiple drug resistance, and pharmacokinetic characteristics. Leveraging
this platform technology, Escugen is rapidly expanding its ADC pipeline
targeting new or validated target. The first ADC product baring the EZWi-Fit® technology
has successfully launched its FIH clinical campaign. In addition, Escugen has
licensed this platform technology to several domestic and international
biotechnology companies to empower their innovative ADC projects.
Source:
Sovran Bio, Inc.