BERKELEY, Calif.--(BUSINESS WIRE)--Plexxikon Inc. today announced that it has submitted an Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) for its lead oncology compound, PLX4032. This targeted anticancer agent selectively inhibits the cancer-causing BRAFV600E gene found in subsets of different cancers, including 70% of malignant melanomas and a significant number of colorectal and thyroid tumors. The company will use a new test to detect the presence of this cancer-causing gene to identify patients most likely to respond to PLX4032, enabling an exquisitely personalized medicine.
