OmniComm Systems, Inc. Ranks Number 284 on [2}'s 2009 Technology Fast 500(TM) for Fastest Growing Companies in North America

FORT LAUDERDALE, FL--(Marketwire - October 20, 2009) -

OmniComm Systems, Inc. (OTCBB: OMCM) today announced that it ranked number 284 on Technology Fast 500™, Deloitte LLP’s ranking of 500 of the fastest growing technology, media, telecommunications, life sciences and clean technology companies in North America. Rankings are based on percentage of fiscal year revenue growth during the five-year period from 2004-2008. OmniComm grew 455% percent during this period.

OmniComm’s CEO, Cornelis F. Wit, credits the company’s flagship product TrialMaster™, and the fact that it was built to the exacting specifications required by the Lifescience industry, for the company’s 455% revenue growth over the past five years. “We are very pleased to be ranked on the Technology Fast 500 list for the second time in the past 5 years,” Mr. Wit said. “This is a testament to the quality of our TrialMaster solution and it illustrates the commitment and vision towards superior customer service embraced by the company as a whole. At OmniComm, we are looking forward to continuing to serve the Lifescience industry with innovative and flexible EDC solutions in their quest for lifesaving therapies and devices.” Mr. Wit added, “The recent additions to our product portfolio of complementary eClinical solutions speaks volumes about our commitment to the industry. We’re not just an EDC shop; we provide a whole array of eClinical solutions and services to our customers.”

“Technology Fast 500™ recognizes innovative companies that have broken down barriers to success and defied the odds with their remarkable five-year revenue growth,” said Phil Asmundson, Vice Chairman and U.S. Technology, Media and Telecommunications leader, Deloitte LLP. “We congratulate OmniComm on this accomplishment.”

“With its impressive five-year growth, OmniComm has earned its position among the fastest growing technology, media, telecommunications, life sciences and clean technology companies in North America,” said Mark Jensen, Managing Partner, Technology and Venture Capital Services, Deloitte & Touche LLP. “Deloitte is proud to honor OmniComm for its achievement.”

OmniComm previously ranked 140th as a Technology Fast 500™ award winner for 2005.

Overall, Technology Fast 500™ award winners for 2009 had growth rates ranging from 212 to 146,050 percent over five years, with an average growth rate of 2,486 percent.

Technology Fast 500™ Selection and Qualifying Criteria

Technology Fast 500™ provides a ranking of the fastest growing technology, media, telecommunications, life sciences and clean technology companies in North America. This ranking is compiled from nominations submitted directly to the Technology Fast 500™ website, and public company database research conducted by Deloitte. Technology Fast 500™ award winners for 2009 are selected based on percentage fiscal year revenue growth during the five-year period from 2004 to 2008. In order to be eligible for Technology Fast 500™ recognition, companies must own proprietary intellectual property or proprietary technology that contributes to a significant portion of the company’s operating revenues. Using other companies’ technology or intellectual property in a unique way does not satisfy this requirement. Consulting companies, professional service firms, etc. are not eligible unless they have proprietary technology that contributes to a significant portion of their operating revenues. Technology Fast 500™ award eligibility requirements also include base-year operating revenues of at least $50,000 USD or CD, and current-year operating revenues of at least $5 million USD or CD. These revenues must have more than doubled between 2004 and 2008. Additionally, companies must be in business for a minimum of five years, and be headquartered within North America.

About OmniComm

OmniComm Systems, Inc. (www.OmniComm.com) provides customer-driven Internet solutions to pharmaceutical, biotechnology, research and medical device organizations that conduct life changing clinical trial research. OmniComm’s growing base of satisfied customers is a direct result of the company’s commitment to deliver products and services that ensure ease of use, faster study build, ease of integration and better performance. OmniComm’s client intuitive pricing model allows companies that range from small, to mid-size to large scale institutions to safely and efficiently capitalize on their clinical research investments. OmniComm Systems, Inc. has U.S. headquarters in Fort Lauderdale, FL and European headquarters in Bonn, Germany, with satellite offices in New Jersey, the United Kingdom, and Russia as well as sales offices throughout the U.S. and Europe.

About Deloitte

“As used in this document, ‘Deloitte’ means Deloitte LLP. Please see www.deloitte.com/about for a detailed description of the legal structure of Deloitte LLP and its subsidiaries.”

Safe Harbor Disclaimer

Statements made by OmniComm included in this release may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements involve a number of risks and uncertainties such as the Company’s ability to obtain new contracts and accurately estimate net revenues due to uncertain regulatory guidance, variability in size, scope and duration of projects, and internal issues at the sponsoring client, integration of acquisitions, competitive factors, technological development, and market demand. As a result, actual results may differ materially from any financial outlooks stated herein. Further information on potential factors that could affect the Company’s financial results can be found in the Company’s Reports on Form 10-K and 10-Q filed with the Securities and Exchange Commission. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events, or otherwise.

CONTACT: Stephen Johnson at: + 1 954-377-1726