EurekAlert -- Tel Aviv, Israel, March 2, 2010 – Newly published data shows using a Respiratory Modulation Response (RMR) is a novel, non-invasive measure to quickly and accurately detect the presence of significant coronary artery disease (sCAD). Patients in the study with sCAD had a lower RMR compared to patients without, regardless of their risk factors or clinical history of angina, previous myocardial infarction (MI), or angioplasty. These data, published in the current issue of Euro Intervention Journal, demonstrate that RMR was lower in patients with significant CAD compared to those with non-significant CAD (P<0.0011), regardless of their risk factors or clinical history of angina, previous MI, or angioplasty.