“New” Human Adenovirus May Not Make for Good Vaccines, After All AdHu26 Demonstrates Same Fault as Previously Studied Vaccine Vectors, The Wistar Institute Study

ScienceDaily (Aug. 11, 2010) — In recent years, scientists have studied the possibility of using engineered human adenoviruses as vaccines against diseases such as HIV, tuberculosis, and malaria. In this approach, adenoviruses, which commonly cause respiratory-tract infections, are rendered relatively harmless before they are used as vectors to deliver genes from pathogens, which in turn stimulate the body to generate a protective immune response.