Osteoarthritis is one of the most draining diseases and so far, no therapy can effectively treat structural deterioration of bones and cartilage or any course of medicine to reverse any existing structural defects.
Osteoarthritis is one of the most draining diseases and so far, no therapy can effectively treat structural deterioration of bones and cartilage or any course of medicine to reverse any existing structural defects. Osteoarthritis is associated with personal and socioeconomic burdens. Thus, several research organizations have been making efforts to identify more tailored treatment options. Osteoarthritis affects at least 27 million people in the U.S. and more than 12% of osteoarthritis cases cause due by earlier injuries.
According to Allied Market Research, the Global Osteoarthritis Treatment Market to reach $15.69 billion by 2030, growing at a CAGR of 8.8% from 2021 to 2030. Rise in the prevalence of osteoarthritis, surge in R&D activities for drug development, and increased geriatric population have boosted the market growth.
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Biological therapy for osteoarthritis:
Biological therapy is one of the promising treatment options for osteoarthritis. It is already used for chronic forms of ankylosing spondylitis (AS) and rheumatoid arthritis (RA). However, there is no clinical validation yet for biological therapy for osteoarthritis.
Currently, chronic forms of osteoarthritis are considered inflammatory diseases instead of wear and tear diseases. It can cause due to growth of nerves and blood vessels from subchondral bone into articular cartilage. Intensive research on the evaluation and development of biological therapy for osteoarthritis could open new opportunities for the treatment and help patients suffering from the painful disease.
Future of osteoarthritis treatment: nanoparticles
For years, regenerative medicine has offered new hope for chronic diseases. It is an umbrella term for the branch of medicine that uses tissue engineering and stem cells to mend tissues that fail to repair themselves. Now, regenerative medicine is not considered as a course of treatment for osteoarthritis. Either by tissue engineering which will try to create a replacement for damaged tissue or by self-healing which will include injections of stem cells to encourage the body to repair itself.
In a novel type of osteoarthritis treatment, nanoparticles are injected shortly after the injury which within 24 hours work taming inflammation in the joint, which may otherwise lead to chronic osteoarthritis. However, unlike steroid injections, these nanoparticles remain in the cartilage cells for weeks, helping the body to heal itself.
Such new treatments offer a unique opportunity to help treat osteoarthritis caused due to inflammation or joint injury. As the treatments are minimally invasive, they are often considered safer to older patients or patients with physical disorders.