PHILADELPHIA--(BUSINESS WIRE)--Integral Molecular, a leader in membrane protein research, announces the issuance of a new composition patent protecting dengue reporter virus particles (RVPs). The invention relates to the company’s chimeric and codon-optimized flavivirus replicons, expression plasmids, and RVPs used for infectivity, neutralization, enhancement and structure-function studies of dengue virus (DENV) and its envelope protein (prM/E). U.S. Patent No 8,691,961, was issued by the USPTO on April 8, 2014, furthering the company’s commitment to the discovery of drugs and vaccines against this widespread virus.
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