Resverlogix Corporation

230 articles with Resverlogix Corporation

• Resverlogix Announces Voting Results from the 2020 Meeting of Shareholders and Update on $13 Million Investment by Sheikh Abdulgader Aboud Baeshen

  12/22/2020

  Resverlogix Corp. (“Resverlogix”, or the "Corporation") (TSX:RVX) today held its Annual and Special Meeting of Shareholders (the “Meeting”) in Calgary, Alberta. During business proceedings at the Meeting, shareholders elected six (6) Board members until the next annual meeting. The voting results of shares represented at the Meeting for individual directors were as follows:                                  Votes For Votes Withheld

• Resverlogix Announces Apabetalone Treatment Prior to SARS-CoV-2 (COVID-19) Exposure Significantly Reduces Viral Infection – Confirms Plans for COVID-19 Clinical Trial

  12/22/2020

  Latest publication confirms BET inhibitors reduce the levels of critical receptors used by SARS-CoV-2 (COVID-19) to gain entry into cells, thereby reducing viral infection

• Resverlogix Announces Publication in High-impact, Peer-reviewed Journal, Clinical Epigenetics

  11/12/2020

  Publication Explores the Beneficial Effects of Apabetalone on the Immune Cells of Diabetic Patients Event Reminder: Multiple Presentations on Apabetalone to be made during the American Heart Association Scientific Sessions

• Resverlogix Reports Filing of New Intellectual Property on Key Renal Protection and Glucose Control Markers

  11/2/2020

  Significantly Strengthens Intellectual Property Portfolio and Apabetalone’s Commercial Runway Position Through 2040 BETonMACE Results Show Significant I mprovement of K ey Markers of Diabetes and Renal Function in the Combination of Apabetalone and SGLT2 inhibitors

• A Second Publication Shortlists Resverlogix Clinical Candidate Apabetalone for its Potential COVID-19 Effectiveness Including Reducing Cytokine Storms

  10/26/2020

  Medicine in Drug Discovery Publication Explores Combination Protein Therapeutics, Including BET Inhibitors, in Preventing Severe Organ Damage from COVID-19 and Reviews Potential Treatments

• Resverlogix Announces Presentations at Leading Scientific ConferencesPresentations on BET Inhibitor Apabetalone to be made during the American Society of Nephrology Kidney Week

  10/15/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today its participation during the following leading scientific conferences: American Society of Nephrology (ASN) Kidney Week Reimagined 2020, 13 th Clinical Trials on Alzheimer's Disease (CTAD) digital event, and the American Heart Association (AHA) Scientific Sessions virtual experience, featuring OnDemand oral presentations on apabetalone. Through participation at le

• Resverlogix Announces Conversion of US$12 Million Debenture Strengthening Balance Sheet

  10/14/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that Vision Leader Limited, a wholly-owned subsidiary of ORI Star Fund LP (“ORI”), has delivered a notice of conversion to convert its entire September 2019 debenture and associated interest, into Resverlogix common shares, which will discharge all security interests associated with the debenture. The US$12 million (approximately CAD$15.8 million) principal amount of the debe

• Resverlogix Announces $13 Million Private Placement

  10/6/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that it has entered into a definitive stock purchase agreement for a private placement of 10,560,000 equity units at a price of $1.25 per unit for gross proceeds of $13.2 million (US$10 million). Each unit will be comprised of one common share and one common share purchase warrant. Each warrant will be exercisable at a price of $1.50 per share for a period of nine mo

• Resverlogix Confirms Interim Filings on SEDAR

  10/2/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announces that, further to its September 25, 2020 press release , it today has filed its interim financial statements and related MD&A for the three months ended July 31, 2020 (the “Interim Filings”). These filings can be found at www.sedar.com  under the Company’s profile . About Resverlogix Resverlogix is developing apabetalone (RVX-208), a first-in-class, small mole

• Resverlogix Announces Publication in High-impact Peer-reviewed Journal – Medicinal Research ReviewsPublication Highlights the Therapeutic Potential of BET Inhibition across Multiple Human Diseases

  9/15/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today the recent publication of an article titled: “ Inhibitors of bromodomain and extra ‐ terminal proteins for treating multiple human diseases” , in the peer-reviewed Medicinal Research Reviews. The publication can be viewed using the following LINK . “We assessed the current understanding of transcriptional mechanisms of BET inhibition to explain why BD2‐sel

• Resverlogix Announces Participation at the Upcoming Global Chinese Financial Forum (“GCFF”) Virtual Conference 2020 – Investing in Innovation

  9/8/2020

  Resverlogix Corp. announces its participation at the GCFF Virtual Conference 2020 - Investing in Innovation on September 10, 2020.

• Resverlogix Announces Publication on Apabetalone in Cardiovascular TherapeuticsCOVID-19 Preclinical Work Continues

  8/4/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) is pleased to announce today the recent publication of an article titled: “ Epigenetic modulation by apabetalone counters cytokine driven acute phase response in vitro , in mice and in patients with cardiovascular disease” , in the peer-reviewed Cardiovascular Therapeutics. The publication can be viewed using the following LINK . “This publication highlights the cutting-edg

• Resverlogix Announces Extension of its Filing Calendar Based on Continuous Disclosure Exemption

  7/28/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announces that it intends to rely on blanket exemptions issued by provincial securities commissions due to the COVID-19 outbreak that permit the Company to extend the filing deadline of certain continuous disclosure documents for a period of up to 45 days. The Company intends to rely on the exemptive relief to extend the date of filing of its annual financial statements for the ye

• Resverlogix Secures One-Year Extension of Maturity Date of Debenture

  7/22/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that it has closed a one-year extension of the maturity date of its debenture. Mr. Donald McCaffrey, President and CEO stated, "We are very pleased that the debenture has been extended for one year, providing us with greater flexibility to create value for our shareholders through both our FDA approved BETonMACE2 final planning and our ongoing partnering discussions.

• Resverlogix Reaches Agreement With FDA for Key Aspects of Apabetalone Registration Enabling Study

  6/22/2020

  Resverlogix Corp. is pleased to announce that the U.S. Food & Drug Administration has accepted its BETonMACE2 clinical plan as a registration enabling study with positive implications for Resverlogix and its ongoing partnership discussions.

• Resverlogix Announces Key BETonMACE Renal Data from Plenary Session Presentation at ERA-EDTA Virtual CongressMACE in the Chronic Kidney Disease group was reduced by 50%

  6/9/2020

  Resverlogix Corp. is pleased to announce key data from its BETonMACE clinical trial in pre-specified stage 3 chronic kidney disease patients.

• Resverlogix Plans COVID-19 Clinical Trial Program LaunchEpigenetic BET-inhibition to combat COVID-19

  6/1/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) is pleased to announce that it is moving forward with a plan to further evaluate apabetalone’s impact on COVID-19 in both a preclinical and clinical setting. A first step will be to investigate whether apabetalone treatment of human cells susceptible to 2019 novel coronavirus (2019-nCoV) infection will impact the replication cycle of the virus. Initial work – undertaken in an ap

• Resverlogix Announces Participation at the American College of Cardiology Scientific Sessions together with the World Congress of Cardiology Virtual

  3/31/2020

  Resverlogix Corp. announced its participation at the American College of Cardiology Scientific Sessions, together with the World Congress of Cardiology, presenting two virtual posters made available on demand via an eAbstracts System starting Saturday, March 28, 2020.

• Resverlogix Announces Publication of Key Apabetalone Study BETonMACE in the Journal of the American Medical Association

  3/30/2020

  Announces publication of accompanying JAMA editorial highlighting important secondary endpoints including congestive heart failure A pabetalone development program moving toward next study to enable a New Drug Application filing CALGARY, Alberta, March 30, 2020 (GLOBE NEWSWIRE) -- Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today the recent publication of an article titled: “ Effect of Apabetalone Added to Standard Therapy on Major Adverse Cardiovas

• Resverlogix Clinical Candidate Apabetalone Featured as a Potential COVID-19 Treatment in Recent PublicationEpigenetic BET-inhibition to combat COVID-19

  3/24/2020

  Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) is pleased to announce a March 23, 2020 bioRxiv publication that has shown apabetalone to inhibit specialized proteins – called bromodomain and extraterminal domain (BET) proteins – from interacting with a SARS-CoV-2 viral protein, with potential for limiting viral reproduction in human cells. The article titled: “ A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Dr