WESTBOROUGH, Mass., Feb. 21, 2014 (GLOBE NEWSWIRE) -- The Society of Surgical Oncology (SSO) and the American Society of Radiation Therapy (ASTRO) have released a consensus guideline for margins in breast conserving surgery. The American Society of Breast Surgeons (ASBS) and the American Society of Clinical Oncology (ASCO) have also endorsed this guideline. The panel concluded that positive margins (detected post-surgery as ink on invasive carcinoma or ductal carcinoma in situ) are associated with a two-fold increase in the risk of ipsilateral breast tumor recurrence (IBTR) compared to negative margins. In December, results of the MarginProbe study were presented at the 2013 CTRC-AACR San Antonio Breast Cancer Symposium, showing a reduction in positive margins originating from the main lumpectomy specimen of over 50% (from 13% to 6%) using the recommended criteria.
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