Discovery Partners International, Inc.'S Chief Executive Officer to Present at SG Cowen & Co. 25th Annual Health Care Conference

SAN DIEGO, March 10 /PRNewswire-FirstCall/ -- Discovery Partners International, Inc. announced today that Riccardo Pigliucci, Chief Executive Officer of Discovery Partners International, Inc. will be presenting at 8:00 AM on Tuesday, March 15, 2005 at the SG Cowen & Co. 25th Annual Health Care Conference being held in Boston, MA Monday, March 14, 2005 through Thursday, March 17, 2005.

The public is invited to participate in the conference live through an audio webcast on the Discovery Partners International, Inc. website at http://www.discoverypartners.com/. A replay of the presentation will be available approximately one (1) hour after the presentation and for ninety (90) days following the live broadcast. The audio webcast will be accessible through a link on the company’s website at http://www.discoverypartners.com/. Presentation materials will be posted on the company’s website.

About Discovery Partners

Discovery Partners International, Inc. is a leader in drug discovery collaborations. DPI offers integrated services, products, and systems that span the drug discovery continuum, including target characterization, targeted and screening-library design and synthesis, high throughput and high content screening, lead generation and optimization, gene expression analysis, and protein crystallization. DPI has actively contributed to dozens of drug discovery collaborations, working on many of the most promising new biological target areas for the biotech and pharmaceutical industries. Discovery Partners International is headquartered in San Diego, California and has operations in the United States, Europe and India. For more information on Discovery Partners International, Inc., please visit the Company’s website at http://www.discoverypartners.com/.

Statements in this press release that are not strictly historical are “forward-looking” statements within the meaning of the Private Securities Litigation Reform Act of 1995 and involve a high degree of risk and uncertainty. Discovery Partners’ actual results may differ materially from those projected in the forward-looking statements due to risks and uncertainties that exist in Discovery Partners’ operations, development efforts and business environment, including the uncertainties more fully described in Discovery Partners’ annual report on Form 10-K for the year ended December 31, 2004 as filed with the Securities and Exchange Commission and Discovery Partners’ other SEC reports.

Discovery Partners International, Inc.

CONTACT: Riccardo Pigliucci, Chief Executive Officer, +1-858-228-4113,ir@discoverypartners.com, or Craig Kussman, Chief Financial Officer,+1-858-228-4113, both of Discovery Partners International