Dermatitis herpetiformis is a chronic autoimmune disorder associated with gluten-sensitive enteropathy. It is a rare disorder linked with celiac disease.
Dermatitis Herpetiformis Market: Introduction
Dermatitis herpetiformis is a chronic autoimmune disorder associated with gluten-sensitive enteropathy. It is a rare disorder linked with celiac disease. This disease was described by Dr. Duhring in 1884, hence it is called Duhring disease or Duhring-Brocq disease.
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It is characterized by the formation of erythematous, urticarial plagues, blisters, and pruritic vesicles. These mostly form on the surface of knees, back, scalp, elbows, and buttocks. The disease can be extremely frustrating for some patients; however, advanced medical facilities and lifestyle modifications have made treatment of dermatitis herpetiformis possible.
The incidence rate of dermatitis herpetiformis in the U.S. is nearly 11.2 people per 100,000 and 75.3 per 100,000 globally. Etiology of the disease includes different factors, genetic and autoimmune. It causes intolerance to the gliadin fraction of gluten protein found in wheat, rye, and barley. Gluten present in the diet triggers formation of immunoglobulin A antibodies, which start autoimmune process against skin and gut. Gastrointestinal disorders may or may not be symptomatic in dermatitis herpetiformis. However, around 90% of affected patients who undergo endoscopic evaluation display gluten-sensitive enteropathy. Moreover, diagnosis requires skin biopsy and treatment involves mostly gluten-free diet. Dapsone provides quick relief in symptoms on the skin.
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Key Drivers, Restraints, and Opportunities of Global Dermatitis Herpetiformis Market
The global dermatitis herpetiformis market is driven by shortage of gluten-free food in some countries, increase in incidence of dermatitis herpetiformis, rise in research & development of new treatment options, and surge in awareness. However, high cost of gluten-free food restrains the global dermatitis herpetiformis market.
The global dermatitis herpetiformis market is driven by increase in number of cases of the disease. The disease could affect patients aged between 15 and 40. The DermNet NZ organization has observed that males are more prone to the disease than females. Patients with dermatitis herpetiformis suffer from severe itchiness. This provides an opportunity for manufacturers to provide products that offer immediate relief. Technological advancements and rigorous research & development by scientists to enhance the quality of drugs and minimize their side effects augment the global dermatitis herpetiformis market.
However, patients are likely to experience dental defects. Additionally, chances are that dermatitis herpetiformis could be mistaken for scabies. Moreover, treatment drugs could lead to anemia, type 1 diabetes, osteoporosis, and thyroid disorders. Furthermore, the global dermatitis herpetiformis market is likely to witness strong growth in the near future, owing to continued investments in development of treatment of the disease.
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North America to Capture Major Share of Global Dermatitis Herpetiformis Market
Geographically, the global dermatitis herpetiformis market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is anticipated to lead the global dermatitis herpetiformis market, followed by Europe.
North America’s dominance of the global market can be attributed to advancements and continuous research and development in the region that would assist patients to opt for better treatment for dermatitis herpetiformis. Moreover, hospitals and diagnostic centers in North America and Europe opt for new technologically advanced methods for the diagnosis of diseases such as dermatitis herpetiformis to enhance the treatment and efficacy of drugs. The dermatitis herpetiformis market in Asia Pacific is expected to grow at a sluggish pace due to low awareness among patients.
Increase in R&D projects in countries in Asia Pacific such as Japan and Australia and the availability of effective drugs for patients suffering from dermatitis herpetiformis are likely to fuel the growth of the market during the forecast period. These countries are projected to be the market leaders in the next few years. The market in regions such as Asia Pacific and Latin America is anticipated to grow at a rapid pace in terms of revenue during the forecast period.
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Key Players Operating in Global Dermatitis Herpetiformis Market
The global dermatitis herpetiformis market is highly fragmented, with the presence of large number of key players. These players hold major market share in their respective regions. Key players identified in the global dermatitis herpetiformis market are Valeant Canada LP, Allergan, GlaxoSmithKline Pharmaceuticals Ltd., Nostrum Laboratories, Inc., and Pfizer, Inc., among others. Companies are involved in collaboration agreements to exploit their maximum potential.
Companies are also strengthening their core competencies and the efficiency of the treatment of dermatitis herpetiformis in their product portfolio. Moreover, research & development is underway to prevent the side effects related to dermatitis herpetiformis treatment, which presents significant opportunities in the market.
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