Cyberonics Inc. Announces Jefferies Life Sciences Conference Presentation

HOUSTON, June 23 /PRNewswire-FirstCall/ -- Cyberonics, Inc. today announced that Cyberonics’ senior management will be attending the Jefferies Life Sciences Conference at the Mandarin Oriental Hotel in New York from June 27-28, 2006. Robert P. (“Skip”) Cummins, Cyberonics’ Chairman of the Board and Chief Executive Officer will present at the conference. Cyberonics’ presentation will occur at 10:45 AM EDT on Tuesday, June 27, 2006. Presentation slides will be available on line at http://www.cyberonics.com by 8:00 AM EDT on Tuesday, June 27, 2006. Jefferies will host a webcast of the presentation live and by replay at http://www.wsw.com/webcast/jeff11/cybx/ or by going to http://www.cyberonics.com and clicking on the link for this webcast. Access to the webcast is not protected by a password.

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Cyberonics, Inc.

CONTACT: Investor Relations of Cyberonics, Inc., +1-281-228-7262, or fax,+1-281-218-9332, or ir@cyberonics.com ; or Helen Shik, Vice President ofSchwartz Communications, +1-781-684-0770, or fax, +1-781-684-6500, orhshik@schwartz-pr.com , for Cyberonics, Inc.

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