CuraGen Corporation To Discuss Fourth Quarter And Year End 2006 Financial Results Via Conference Call On February 1, 2007

BRANFORD, Conn., Jan. 25 /PRNewswire-FirstCall/ -- CuraGen Corporation today announced that Company executives will be holding a conference call to discuss CuraGen and 454 Life Sciences’ fourth quarter and year end 2006 financial results at 11:00 a.m. Eastern Standard Time on Thursday, February 1, 2007. A press release outlining 2006 results and 2007 financial guidance for CuraGen and 454 Life Sciences will be issued prior to the call.

Date: Thursday, February 1, 2007 Time: 11:00 a.m. EST Dial-in: 877-272-5391 (domestic) 706-758-4315 (international) Passcode: 6402882 Webcast: Access to the live webcast is at http://www.curagen.com.

A replay of the conference call will be available starting at 2:00 p.m. Eastern Standard Time on Thursday, February 1, 2007 through Thursday, March 1, 2007 by dialing 800-642-1687 (domestic) or 706-645-9291 (international). The passcode for the replay is 6402882. An archive of the webcast will be available for 30 days at http://www.curagen.com.

About CuraGen

CuraGen Corporation is a biopharmaceutical company developing diverse approaches, including novel protein, antibody, and small molecule therapeutics, that aim to offer hope for patients with cancer, inflammatory diseases, and diabetes. CuraGen’s strategic alliances have resulted in a deep pipeline of potential therapeutics that is being developed by the Company’s experienced research and development teams. By leveraging the drug development strengths cultivated over the years, CuraGen expects to make a difference in the lives of patients by bringing forward promising therapeutics that address unmet medical needs. To further capitalize on CuraGen’s extensive research and development expertise, CuraGen founded a majority-owned subsidiary, 454 Life Sciences, which has developed and is commercializing advanced technologies for the sequencing of DNA. CuraGen is headquartered in Branford, Connecticut. For additional information please visit www.curagen.com.

CuraGen Contact: Glenn Schulman, Pharm.D. Director of Investor Relations gschulman@curagen.com (888) 436-6642 CRGN-F

CuraGen Corporation

CONTACT: Glenn Schulman, Pharm.D., Director of Investor Relations ofCuraGen Corporation, +1-888-436-6642, or gschulman@curagen.com

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