University of Minnesota Researchers Use Stem Cells to Treat Children With Life-Threatening, Blistering Skin Disease

Eurekalert -- University of Minnesota Physician-researchers have demonstrated that a lethal skin disease can be successfully treated with stem cell therapy. Medical School researchers John E. Wagner, M.D., and Jakub Tolar, M.D., Ph.D., in collaboration with researchers in Portland, Oregon, the United Kingdom, and Japan have for the first time used stem cells from bone marrow to repair the skin of patients with a fatal skin disease called recessive dystrophic epidermolysis bullosa, or RDEB. This is the first time researchers have shown that bone marrow stem cells can home to the skin and upper gastrointestinal tract and alter the natural course of the disease.