Cough Hypersensitivity Syndrome Treatment Market: Manufacturers Collaborating with Healthcare Providers to Increase Awareness about Early Upper Endoscopy
Companies Invest in Opiates and GABA-Related Compounds to Treat Cough Hypersensitivity Syndrome
On a global level, the alarming prevalence of chronic cough amongst individuals has propelled healthcare companies in the cough hypersensitivity syndrome treatment market to develop efficacious treatment options. As such, they are increasing their focus on developing improved formulations of antitussive agents. This trend is distinctly true, since antitussive agents are projected to dominate the cough hypersensitivity syndrome treatment market, with an estimated revenue of ~US$ 2.8 billion by 2027.
In order to relieve patients from cough hypersensitivity, healthcare companies are investing in opiates and GABA (gamma-aminobutyric acid)-related compounds. Opiates serve as effective cough suppressants and possess efficacious antitussive properties to treat chronic intractable cough. Likewise, companies are increasing their production capabilities of tramadol, an opioid medication that is similar to the molecular formula of codeine drugs.
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Since chronic cough causes increased body pain, companies in the cough hypersensitivity syndrome treatment market are increasing the availability of babapentin and pregabalin, which are GABA-related compounds, and act as neuromodulators for the treatment of neuropathic pain and epilepsy. It has been found in placebo-controlled trials that, gabapentin is well-tolerated for the treatment of refractory chronic cough.
PPI Therapy and Beta Agonists Provide Relief for GERD and Asthma
Healthcare companies in the cough hypersensitivity syndrome treatment space are increasing clinical trials to study the effects of aerosolized capsaicin with behavioral cough suppression. It has been found that, the inhalation of aerosolized capsaicin in gradually increasing doses has contributed to the decrease in cough sensitivity. Healthcare providers have recommended the repetition of the treatment sessions to effectively minimize the instances of cough hypersensitivity.
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Chronic cough is associated with high prevalence of gastroesophageal reflux disease (GERD). Hence, companies in the cough hypersensitivity syndrome treatment market are innovating in proton pump inhibitors (PPI) therapy. Proton pump inhibitors currently account for the second-highest revenue share amongst the drugs in the cough hypersensitivity syndrome treatment market.
PPI therapy is also effective for diseases related to GERD, such as achalasia, infectious esophagitis, and eosinophilic esophagitis. In order to treat asthma, healthcare providers in the cough hypersensitivity syndrome treatment market are increasing research capabilities in bronchodilators that include short acting beta-2 agonists. They also recommend patients to undergo spirometry to avoid the side effects of beta agonists.
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Manufacturers Collaborating with Healthcare Providers to Increase Awareness about Early Upper Endoscopy
The cough hypersensitivity syndrome treatment market is anticipated to grow at a modest CAGR of ~5%. However, the nature of the market is consolidated, which makes it challenging for emerging market players to enter into the bracket of prominent and leading healthcare companies. Although the market is consolidated, the inefficiency of drugs and their adverse effects are negatively affecting market growth.
For instance, voltage-gated sodium channels reduce excitability and sensory nerve activity amongst patients. However, there is a growing need for newer agents that present realistic options for cough hypersensitivity syndrome patients. In many cases, proton pump inhibitors lead to complications of refractory GERD, with recurrence of reflux symptoms.
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Hence, healthcare companies in the cough hypersensitivity syndrome treatment market should increase awareness about the judicious administration of PPIs. They should team up with healthcare providers who can encourage patients to undergo early upper endoscopy to evaluate new alarm symptoms.
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