Cell Reprogramming Market Size, Trends, Share, Growth, Report 2022-2030

According to Vision Research Reports, the global cell reprogramming market size was accounted at USD 311.7 million in 2021 and it is predicted to surpass around USD 626.2 million by 2030 with a CAGR of 8.06% from 2022 to 2030.

Cell Reprogramming Market Size 2021 to 2030

Report Highlights

  • The mRNA technology segment accounted for the highest share of more than 36.21% of the overall revenue in 2021. 
  • The research application segment dominated the industry in 2021 and accounted for the highest share of more than 80.4% of the overall revenue. 
  • The research & academic institutes segment dominated the global industry in 2021 and accounted for the highest share of more than 36.21% of the overall revenue. 
  • North America dominated the industry in 2021 and accounted for the largest share of 35.3% of the total revenue. 

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Cell reprogramming is known for its capacity to replace damaged cells or tissues, thereby reversing the negative physiological effects it causes. The industry is driven by the growing interest among researchers in the field for the reason that it makes it possible to see and evaluate molecular biological mechanisms like differentiation, epigenetics, and chromatin in ways that were formerly impossibly complex. Furthermore, cellular reprogramming also has a substantial impact on diagnosing and addressing human diseases. Moreover, reprogramming technology is being created & improved; there have also been substantial ongoing advancements in related technologies like gene editing, creation of progenitor cells, & tissue engineering.

The pharmaceutical industry is projected to use the iPSC approach widely to generate effective cell sources, such as iPSC-derived functional cells, to enable drug screening and toxicity assessment. Thus, the growing use of iPSC across the world would propel the demand for cell reprogramming resulting in industry growth. The increase in clinical trials and the wide usage of stem cell therapies around the world are fueling the industry's expansion. Various academic institutions, biotech & pharmaceutical companies, and government agencies from different nations are focusing on efficient and quick methods for the detection of COVID-19. Mesenchymal stem cells are a safe and efficient method for treating COVID-19, according to a 2020 research article that was published in the academic journal Aging and Disease (2020).

In addition, the lack of efficient treatment for COVID-19 has sparked the attention of the healthcare industry on cell reprogramming technology. As a result, the usage of cell reprogramming technologies is projected to increase during the COVID-19 pandemic. Despite the fact that mesenchymal cells and iPSCs are used in cell reprogramming, there are still several challenges that prevent the market from expanding. The main causes for concern are people’s lack of knowledge about the available treatments and their dread of the unknown therapy. On the other hand, the industry is positioned for growth as a result of the widening pipeline of stem cell therapies, growing interest in customized treatments, and rising healthcare spending. Moreover, the lenient rules that govern stem cell reprogramming in India may play a significant role in luring more businesses to invest in, develop, and market innovative technologies, fueling the continued expansion.

Scope of The Report

Report Coverage

Details

Market Size in 2021

USD 311.7 million

Revenue Forecast by 2030

USD 626.2 million

Growth rate from 2022 to 2030

CAGR of 8.06%
 

Base Year

2021

Forecast Period

2022 to 2030

Segmentation

Technology, application, end-use, region
 

Companies Covered

Allele Biotechnology; Alstem; Applied Biological Materials; Axol Bioscience; Creative Bioarray; DefiniGEN; Fujifilm Cellular Dynamics; Lonza; Mogrify; Reprocell; Stemnovate; Thermo Fisher Scientific

 

Technology Insights

The mRNA technology segment accounted for the highest share of more than 36.21% of the overall revenue in 2021. This technology is easy to use and offers a quick, secure, & effective way to create human iPS cells of the highest quality from somatic tissue. It also provides a reprogramming efficiency of better than 1% and an advantage when working with difficult-to-reprogram samples. For instance, according to an article published in February 2021, synthetic mRNA cell reprogramming is an accurate and reliable method to generate human iPSCs. Sendai virus-based reprogramming is also anticipated to expand at a significant growth rate during the projected period.

As it generates cell reprogramming at a steady rate and has technological superiorities over other techniques, it has a high adoption rate among patients and is widely used in clinical studies of gene therapy and vaccine delivery. For instance, in May 2018, a Sendai virus reprogrammed system was developed by the International Society of Cell and Gene Therapy for use in clinical and translational studies. In addition, techniques were developed using the Sendai antibody for the detection and removal of undesirable cells, as well as qPCR-based SeV quantification to ensure that the clones produced were footprint-free. Furthermore, increased chronic disease incidences continued technological advancements in reprogramming technology, and rising awareness in emerging nations are primary growth drivers.

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Application Insights

On the basis of applications, the global industry has been further bifurcated into research and therapeutic. The research application segment dominated the industry in 2021 and accounted for the highest share of more than 80.4% of the overall revenue. One of the main drivers fueling segment growth is an ongoing research area in the field of cell reprogramming with the help of stem cells. Governments as well as other private groups are funding considerable stem cell research studies, which is pushing the industry participants to carve their niches in the global sector by treating a range of chronic conditions.

For instance, 64% of Americans support federal financing for chronic disease research using stem cells from human embryos. Thus, research efforts are anticipated to supplement the segment growth. Cell reprogramming has already opened up incredible possibilities for therapeutics, such as new drug treatments that inhibit degenerative changes or encourage stem or progenitor cells to distinguish the difference in the affected lineage in a particular condition, which are both possible as a result of reprogramming studies. Some degenerative disorders might also be treatable with cell transplantation. The speed and breadth of these developments are promoting segment growth.

End-use Insights

On the basis of end-uses, the global industry has been further categorized into research & academic institutes, biotechnology & pharmaceutical companies, and hospitals & clinics. The research & academic institutes segment dominated the global industry in 2021 and accounted for the highest share of more than 36.21% of the overall revenue. Cell reprogramming has recently been transferred from the lab to the clinic by researchers. In numerous clinical and academic research projects, including those involving regenerative medicine, disease modeling, and medication toxicity/drug discovery studies, cell reprogramming has been used.

Furthermore, the clinical application of this technology is greatly facilitated by the use of cell reprogramming in regenerative medicine. This is linked to the growing research efforts examining the effectiveness and safety of cell reprogramming, which have helped the category flourish. The segment is also expected to be driven by an increase in the number of strategic efforts for research and method for innovative products from cell reprogramming. For instance, The California Institute for Regenerative Medicine has encouraged various research groups to contribute funds for cellular reprogramming’s transition to therapeutic applications and a clinical focus.

Regional Insights

North America dominated the industry in 2021 and accounted for the largest share of 35.3% of the total revenue. The high share can be attributed to the ongoing iPSC technology advancements and the availability of functional cells for pre-clinical drug testing. High throughput drug toxicity analysis and expanding knowledge of the iPSC platform both contribute to the region’s expansion. In the U.S., activities in medical research have increased as a result of the growing need for innovative treatment options. One of the main areas of attention is stem cell research, hence the requirement for cell reprogramming has been favored by this expanded study.

For instance, in April 2022, to help the iPSC reprogramming industry expansion, Ncardia announced the opening of a new company named Cellistic. Its emphasis and proficiency in differentiation, iPSC reprogramming, and other areas aid in market growth. Asia Pacific is estimated to be the fastest-growing region due to the improvements in production & the efficiency of the therapy landscape. The COVID-19 pandemic has further fueled the market growth in Asia Pacific on account of the large patient population base and there are currently no effective treatments for the infection, particularly in severe cases.

Genomic variants are the main cause of a wide variety of variability in the clinical symptoms of patients. Consequently, it is acknowledged that individualized care can effectively address these symptoms. As a result, the region is growing due to the increased adoption of cell reprogramming technologies. In addition, the expansion of medical development frameworks and better healthcare systems in developing nations like Australia and India has set the Asia Pacific region up to see lucrative growth over the period.

Key Players

  • Allele Biotechnology
  • ALSTEM
  • Applied Biological Materials
  • Axol Bioscience
  • Creative Bioarray
  • DefiniGEN
  • Fujifilm Cellular Dynamics
  • Lonza
  • Mogrify
  • REPROCELL
  • Stemnovate
  • Thermo Fisher Scientific

Market Segmentation

  • By Technology Outlook
    • Sendai virus-based Reprogramming
    • mRNA Reprogramming
    • Episomal Reprogramming
    • Others
  • By Application Outlook
    • Research
    • Therapeutic
  • By End-use Outlook
    • Research & Academic Institutes
    • Biotechnology & Pharmaceutical Companies
    • Hospitals & Clinics
  • By Regional Outlook
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East & Africa

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