The biological complexity of bone marrow is driven by the diverse array of hematopoietic and non-hematopoietic cells that orchestrate intricate biological activities, such as immune and tumor regulation, as well as hematopoiesis. Observing and tracking the complex cellular interactions and activities within the bone marrow niche are limited by currently available techniques, such as blood counts and histology, which use a “snapshot” of static evidence to infer such dynamics in vivo.
