BioSpace News Archive

Angela Justice, Ph.D., is a leadership coach and former biotech executive who helps leaders earn—and embrace—their seat at the table with coaching grounded in behavioral science and real-world experience. You can follow her on LinkedIn.

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Cell therapy

5 CAR T Cell Therapies With Autoimmune Readouts in 2025

Having established success in cancer, biopharma is now looking to leverage CAR T therapies against a new target, autoimmune disorders, with several early- to mid-stage readouts expected this year.

March 17, 2025

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9 min read

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Tristan Manalac

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Opinion

Angelman Syndrome Race Heats Up Among Ionis, Ultragenyx and Neuren

Ionis and Ultragenyx are competing to develop oligonucleotide treatments for Angelman syndrome, but will Neuren’s peptide catch up?

March 17, 2025

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3 min read

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Jia Jie Chen

Legal

Regeneron Loses Appeal to Block Amgen’s Eylea Biosimilar

The appeals court for the Federal Circuit upheld a lower court’s ruling, finding that Regeneron has not sufficiently established that Amgen’s biosimilar Pavblu violates key patents of Eylea.

March 17, 2025

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2 min read

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Tristan Manalac

AstraZeneca's sign on its office in California

Mergers & acquisitions

AstraZeneca Makes Potential $1B Cell Therapy Play in EsoBiotec Buy

AstraZeneca has recently been investing heavily in the cell therapy space, including two acquisitions for TeneoTwo and Gracell Biotechnologies.

March 17, 2025

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2 min read

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Tristan Manalac

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GLP-1

Altimmune Jumps On Takeover Rumors After Launching Alcohol Use Disorder Study

The company unveiled plans last week to test its GLP-1/glucagon dual receptor agonist in alcohol use disorder and alcohol-related liver disease.

March 17, 2025

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1 min read

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Tristan Manalac

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GLP-1

GLP-1 Players Seek to Differentiate in Increasingly Crowded Weight Loss Space

As obesity drug developers compete for the highest weight-loss efficacy, experts contend that overall health outcomes—evidenced by successful studies in therapeutic areas like cardiovascular and sleep apnea—may prove a greater market advantage.

March 17, 2025

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6 min read

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Kate Goodwin

Duchenne muscular dystrophy

Dyne’s Duchenne Exon Skipping Oligomer Shows ‘Differentiated’ Clinical Effect

Dyne is eyeing an accelerated approval filing for DYNE-251 in early 2026 that would pit the asset against Sarepta’s Exondys 51 in a patient population amenable to exon 51 skipping.

March 17, 2025

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2 min read

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Tristan Manalac