Xeris Pharmaceuticals Announces Dosing of First Patient in Phase 2 Clinical Trial of its Investigational Soluble Glucagon Formulation

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AUSTIN, Texas, Oct. 17, 2013 (GLOBE NEWSWIRE) -- Xeris Pharmaceuticals, Inc. (“Xeris”), a clinical stage, specialty biopharmaceutical company developing novel non-aqueous formulations of injectable drugs, announced today the dosing of the first subject in a Phase 2 clinical study of the company’s stable liquid glucagon in normal healthy volunteers. Xeris’ G-Pen™ (glucagon injection) has potential as a room temperature stable, “ready to inject” glucagon for the treatment of severe hypoglycemia in people with diabetes. The currently approved glucagon emergency kits (GEKs) marketed by Eli Lilly and Company and Novo Nordisk contain glucagon as a dry powder in a sealed vial, which must be reconstituted in a multi-step process with a water-filled syringe prior to injection. Xeris’ glucagon formulation does not require reconstitution as it is pre-mixed, allowing for administration in only two steps.

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