Travellers’ Diarrhoea (TD) frequently occurs in individuals from industrialised countries when visiting destinations in developing countries. Consequences of TD include disruption of holiday and work capacity, and occasionally severe chronic disease. Existing methods of prevention are inadequate. We calculate that the number of travellers to TD risk regions was 88 million in 2003 and may reach 190 million per annum by 2020, suggesting that a significant potential market exists for a TD vaccine.
