The global transfer membrane market size was USD 181 million in 2020 and is expected to register a CAGR of 1.7% during the forecast period.
The global transfer membrane market size was USD 181 million in 2020 and is expected to register a CAGR of 1.7% during the forecast period. Steady global market revenue growth is attributed to various factors such as significant increase in prevalence of new and target diseases worldwide, surging research & development activities in pharmaceutical and biotechnological industries globally, and increased public and private investments in the life sciences industry.
Rising focus on new drug discovery and development, emergence of novel DNA and RNA-based drug therapies, and advancements in membrane transfer technologies such as greater variety of detection chemicals and higher straining capability are other key factors propelling growth of the transfer membrane market. Furthermore, market growth is supported by rising incidence of autoimmune diseases and increasing applications of transfer membranes in protein sequencing, western blotting, etc.
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A transfer membrane is a microporous membrane that is used to transfer proteins and biomolecules from gel matrices for staining and detection of antibodies. The proteins are transferred by passing a current to the transfer membrane through gel. These membranes bind perfectly with the biomolecules to facilitate the process of protein transfer. Membrane transport plays a vital role in cellular biology and involves a number of mechanisms that aid in regulating the passage of various solutes such as ions and biomolecules via biological membranes. These membranes are made up of lipid bilayers that contain proteins and are characterized by selective membrane permeability that helps these membranes separate various chemical substances. Transfer membranes find significant applications in various processes such as western blotting, northern blotting, southern blotting, and protein sequencing. They are also widely used in capillary action techniques to aid in the separation of DNA, RNA, and protein fragments for staining and detection. Specific advantages of transfer membranes are compatibility with several detection chemistry techniques and superior staining capabilities. Polyvinylidene Difluoride (PVDF) transfer membranes, nitrocellulose transfer membranes, and nylon transfer membranes are among the most widely used types. Nylon membranes find widespread use in northern blotting and southern blotting for nucleic acid binding, while PVDF membranes are extensively used in western blotting for robust protein transfer. Moreover, nitrocellulose membranes are used in protein sequencing due to their high protein binding and retention capacities.
Global Transfer Membrane Market: Dynamics
Drivers: Rising demand for PVDF transfer membranes due to specific advantages is a crucial market growth driver
Rising demand for PVDF membranes for specific advantages offered by them is one of the most vital factors accountable for the global transfer membrane market growth. PVDF membranes are hydrophobic in nature and are characterized by superior binding affinity for nucleic acids and proteins and higher sensitivity for small peptides. They are more preferred than nylon and nitrocellulose membranes due to better retention capacity for adsorbed proteins. Hence, increasing protein analysis applications of these products including western blotting, northern blotting, southern blotting, and protein sequencing, is further boosting market growth.
Restraints: Disadvantages associated with nitrocellulose and nylon membranes are predicted to hamper market growth
Specific disadvantages associated with nitrocellulose and nylon membranes are expected to restrict the growth of the global transfer membrane market to a significant extent. These membranes have relatively lower mechanical strength and become brittle when dry. They are not suitable for multiple stripping and reprobing. Moreover, these membranes have significantly lesser chemical compatibility and protein retention capacity than PVDF membranes.
Global Transfer Membrane Market: Type Outlook
Based on type, the global transfer membrane market is segmented into PVDF transfer membranes, nylon transfer membranes, and nitrocellulose transfer membranes. The PVDF transfer membranes segment is projected to hold the highest revenue share of the market in the upcoming years, mainly owing to increasing applications of these membranes in western blotting and rising awareness of advantages of PVDF over other membranes, such as superior chemical compatibility and more enhanced protein retention capacity. Other significant advantages of PVDF membranes such as greater physical strength and higher chemical compatibility as compared to nitrocellulose and nylon membranes, further boost this segment’s growth.
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Global Transfer Membrane Market: End-use Outlook
The global transfer membrane market comprises various end-users including pharmaceutical and biotechnology companies, diagnostic laboratories, academic & research institutes, and others. The academic & research institutes segment is expected to account for largest market revenue share over the forecast period. Factors influencing revenue growth of this segment include increasing research collaborations between academic institutions and top pharmaceutical companies and augmented financial support by government bodies for research & development programs being conducted in the life sciences sector.
Global Transfer Membrane Market: Regional Outlook
The global transfer membrane market is segmented region-wise into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. North America is expected to account for leading market share over the forecast period. Robust presence of leading transfer membrane companies in countries in the region, rising prevalence of chronic and target diseases, and increasing focus of biopharmaceutical companies on proteomic and genomic research. The region’s consistently advancing healthcare infrastructure and increasing government investments in life sciences R&D activities are expected to further bolster growth of the North America market going ahead.
Companies Profiled in the Report:
Merck KGaA, Thermo Fisher Scientific, PerkinElmer, Bio-Rad Laboratories, GE Healthcare, Pall Corporation, GVS, Azure Biosystems, Santa Cruz Biotechnology, Abcam, Axiva Sichem Biotech, ATTO Corporation, Advansta, Macherey-Nagel, and Carl Roth are among the key players in the global transfer membrane market. These firms are undertaking various strategic initiatives such as mergers & acquisitions, collaborations, joint ventures, and new business deals, to strengthen their market positions and drive revenue growth.
Key Developments:
- In June 2020, biotech major Creative Biostructure upgraded its membrane protein service for the pharmaceutical industry. Cell membrane acts as a boundary that separates the cell from the outer environment. Through membrane proteins, various nutrients, ions, and even DNA and proteins are transferred into cells. Moreover, membrane protein plays an integral role in cell function and is often considered as the most suitable drug target.
Global Transfer Membrane Market Segmentation:
For the purpose of this report, the global transfer membrane market has been segmented based on type, transfer method, application, end-use, and region:
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Transfer Membrane Market Report Scope
Segments covered By Type Outlook, Transfer Method, Application, End-use, Regional Outlook
By Type Outlook
- PVDF (Polyvinylidene Fluoride) Transfer Membrane
- Nitrocellulose Transfer Membrane
- Nylon Transfer Membrane
By Transfer Method
- Tank Electrotransfer
- Dry Electrotransfer
- Semi-dry Electrotransfer
- Others
By Application
- Western Blotting
- Southern Blotting
- Northern Blotting
- Protein Sequencing
- Amino Acid Analysis
- Others
By End-use
- Pharmaceutical and Biotechnology Companies
- Diagnostic Laboratories
- Academic & Research Institutes
- Others
Regional scope
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
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