The future use of a gene-based technology called pharmacogenomics could lower the cost of health care by decreasing the occurrence of adverse drug effects and increasing the probability of successful therapy. These findings are published by investigators at St. Jude Children’s Research Hospital in the May 27 issue of Nature. According to the authors, the significant potential for improving health and reducing cost will not be achieved unless three things happen. First, more studies must be undertaken to identify the network of genes that govern most drug responses. Second, systems must be developed to assist physicians and pharmacists in interpreting genetic tests for selecting drug therapy. Finally, legal protections must be put in place to preclude the misuse of genetic information from patients.